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Exploration of the Dynamic Properties of Protein Complexes Predicted from Spatially Constrained Protein-Protein Interaction Networks

Protein complexes are not static, but rather highly dynamic with subunits that undergo 1-dimensional diffusion with respect to each other. Interactions within protein complexes are modulated through regulatory inputs that alter interactions and introduce new components and deplete existing component...

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Detalles Bibliográficos
Autores principales: Yen, Eric A., Tsay, Aaron, Waldispuhl, Jerome, Vogel, Jackie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038459/
https://www.ncbi.nlm.nih.gov/pubmed/24874694
http://dx.doi.org/10.1371/journal.pcbi.1003654