Inferring Host Gene Subnetworks Involved in Viral Replication

Systematic, genome-wide loss-of-function experiments can be used to identify host factors that directly or indirectly facilitate or inhibit the replication of a virus in a host cell. We present an approach that combines an integer linear program and a diffusion kernel method to infer the pathways th...

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Detalles Bibliográficos
Autores principales: Chasman, Deborah, Gancarz, Brandi, Hao, Linhui, Ferris, Michael, Ahlquist, Paul, Craven, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038467/
https://www.ncbi.nlm.nih.gov/pubmed/24874113
http://dx.doi.org/10.1371/journal.pcbi.1003626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038467/
https://www.ncbi.nlm.nih.gov/pubmed/24874113
http://dx.doi.org/10.1371/journal.pcbi.1003626

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