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Exploring the Potential of Flubendazole in Filariasis Control: Evaluation of the Systemic Exposure for Different Pharmaceutical Preparations

The goal of elimination of the human filariases would benefit greatly from the use of a macrofilaricidal agent. In vivo trials in humans and many experimental animal models suggest that flubendazole (FLBZ) is a highly efficacious macrofilaricide. However, since serious injection site reactions were...

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Detalles Bibliográficos
Autores principales: Ceballos, Laura, Mackenzie, Charles, Geary, Timothy, Alvarez, Luis, Lanusse, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038472/
https://www.ncbi.nlm.nih.gov/pubmed/24874646
http://dx.doi.org/10.1371/journal.pntd.0002838