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Protein tyrosine phosphatases ε and α perform nonredundant roles in osteoclasts

Female mice lacking protein tyrosine phosphatase ε (PTP ε) are mildly osteopetrotic. Osteoclasts from these mice resorb bone matrix poorly, and the structure, stability, and cellular organization of their podosomal adhesion structures are abnormal. Here we compare the role of PTP ε with that of the...

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Detalles Bibliográficos
Autores principales: Finkelshtein, Eynat, Lotinun, Sutada, Levy-Apter, Einat, Arman, Esther, den Hertog, Jeroen, Baron, Roland, Elson, Ari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038506/
https://www.ncbi.nlm.nih.gov/pubmed/24694598
http://dx.doi.org/10.1091/mbc.E14-03-0788