Cargando…
The Continual Reassessment Method for Multiple Toxicity Grades: A Bayesian Model Selection Approach
Grade information has been considered in Yuan et al. (2007) wherein they proposed a Quasi-CRM method to incorporate the grade toxicity information in phase I trials. A potential problem with the Quasi-CRM model is that the choice of skeleton may dramatically vary the performance of the CRM model, wh...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038518/ https://www.ncbi.nlm.nih.gov/pubmed/24875783 http://dx.doi.org/10.1371/journal.pone.0098147 |