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The Continual Reassessment Method for Multiple Toxicity Grades: A Bayesian Model Selection Approach

Grade information has been considered in Yuan et al. (2007) wherein they proposed a Quasi-CRM method to incorporate the grade toxicity information in phase I trials. A potential problem with the Quasi-CRM model is that the choice of skeleton may dramatically vary the performance of the CRM model, wh...

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Detalles Bibliográficos
Autores principales:	Pan, Haitao, Zhu, Cailin, Zhang, Feng, Yuan, Ying, Zhang, Shemin, Zhang, Wenhong, Li, Chanjuan, Wang, Ling, Xia, Jielai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038518/ https://www.ncbi.nlm.nih.gov/pubmed/24875783 http://dx.doi.org/10.1371/journal.pone.0098147

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