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Combination of Gefitinib and DNA Methylation Inhibitor Decitabine Exerts Synergistic Anti-Cancer Activity in Colon Cancer Cells

Despite recent advances in the treatment of human colon cancer, the chemotherapy efficacy against colon cancer is still unsatisfactory. In the present study, effects of concomitant inhibition of the epidermal growth factor receptor (EGFR) and DNA methyltransferase were examined in human colon cancer...

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Detalles Bibliográficos
Autores principales: Lou, Yun-feng, Zou, Zheng-zhi, Chen, Pin-jia, Huang, Guo-bin, Li, Bin, Zheng, De-qing, Yu, Xiu-rong, Luo, Xiao-yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038521/
https://www.ncbi.nlm.nih.gov/pubmed/24874286
http://dx.doi.org/10.1371/journal.pone.0097719