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The Evolutionarily Conserved Mediator Subunit MDT-15/MED15 Links Protective Innate Immune Responses and Xenobiotic Detoxification

Metazoans protect themselves from environmental toxins and virulent pathogens through detoxification and immune responses. We previously identified a small molecule xenobiotic toxin that extends survival of Caenorhabditis elegans infected with human bacterial pathogens by activating the conserved p3...

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Detalles Bibliográficos
Autores principales: Pukkila-Worley, Read, Feinbaum, Rhonda L., McEwan, Deborah L., Conery, Annie L., Ausubel, Frederick M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038581/
https://www.ncbi.nlm.nih.gov/pubmed/24875643
http://dx.doi.org/10.1371/journal.ppat.1004143