A New Class of Multimerization Selective Inhibitors of HIV-1 Integrase

The quinoline-based allosteric HIV-1 integrase (IN) inhibitors (ALLINIs) are promising candidates for clinically useful antiviral agents. Studies using these compounds have highlighted the role of IN in both early and late stages of virus replication. However, dissecting the exact mechanism of actio...

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Detalles Bibliográficos
Autores principales: Sharma, Amit, Slaughter, Alison, Jena, Nivedita, Feng, Lei, Kessl, Jacques J., Fadel, Hind J., Malani, Nirav, Male, Frances, Wu, Li, Poeschla, Eric, Bushman, Frederic D., Fuchs, James R., Kvaratskhelia, Mamuka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038613/
https://www.ncbi.nlm.nih.gov/pubmed/24874515
http://dx.doi.org/10.1371/journal.ppat.1004171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038613/
https://www.ncbi.nlm.nih.gov/pubmed/24874515
http://dx.doi.org/10.1371/journal.ppat.1004171

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