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A New Class of Multimerization Selective Inhibitors of HIV-1 Integrase
The quinoline-based allosteric HIV-1 integrase (IN) inhibitors (ALLINIs) are promising candidates for clinically useful antiviral agents. Studies using these compounds have highlighted the role of IN in both early and late stages of virus replication. However, dissecting the exact mechanism of actio...
Autores principales: | Sharma, Amit, Slaughter, Alison, Jena, Nivedita, Feng, Lei, Kessl, Jacques J., Fadel, Hind J., Malani, Nirav, Male, Frances, Wu, Li, Poeschla, Eric, Bushman, Frederic D., Fuchs, James R., Kvaratskhelia, Mamuka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038613/ https://www.ncbi.nlm.nih.gov/pubmed/24874515 http://dx.doi.org/10.1371/journal.ppat.1004171 |
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