Ly49C-Dependent Control of MCMV Infection by NK Cells Is Cis-Regulated by MHC Class I Molecules

Natural Killer (NK) cells are crucial in early resistance to murine cytomegalovirus (MCMV) infection. In B6 mice, the activating Ly49H receptor recognizes the viral m157 glycoprotein on infected cells. We previously identified a mutant strain (MCMV(G1F)) whose variant m157 also binds the inhibitory...

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Detalles Bibliográficos
Autores principales: Forbes, Catherine A., Scalzo, Anthony A., Degli-Esposti, Mariapia A., Coudert, Jerome D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038614/
https://www.ncbi.nlm.nih.gov/pubmed/24873973
http://dx.doi.org/10.1371/journal.ppat.1004161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038614/
https://www.ncbi.nlm.nih.gov/pubmed/24873973
http://dx.doi.org/10.1371/journal.ppat.1004161

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