Cargando…
Ly49C-Dependent Control of MCMV Infection by NK Cells Is Cis-Regulated by MHC Class I Molecules
Natural Killer (NK) cells are crucial in early resistance to murine cytomegalovirus (MCMV) infection. In B6 mice, the activating Ly49H receptor recognizes the viral m157 glycoprotein on infected cells. We previously identified a mutant strain (MCMV(G1F)) whose variant m157 also binds the inhibitory...
Autores principales: | Forbes, Catherine A., Scalzo, Anthony A., Degli-Esposti, Mariapia A., Coudert, Jerome D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038614/ https://www.ncbi.nlm.nih.gov/pubmed/24873973 http://dx.doi.org/10.1371/journal.ppat.1004161 |
Ejemplares similares
-
The complex of MCMV proteins and MHC class I evades NK cell control and drives the evolution of virus-specific activating Ly49 receptors
por: Železnjak, Jelena, et al.
Publicado: (2019) -
The Impact of Ly49-NK Cell-Dependent Recognition of MCMV Infection on Innate and Adaptive Immune Responses
por: Pyzik, Michal, et al.
Publicado: (2011) -
“Natural Regulators”: NK Cells as Modulators of T Cell Immunity
por: Schuster, Iona S., et al.
Publicado: (2016) -
M144, a Murine Cytomegalovirus (Mcmv)-Encoded Major Histocompatibility Complex Class I Homologue, Confers Tumor Resistance to Natural Killer Cell–Mediated Rejection
por: Cretney, Erika, et al.
Publicado: (1999) -
MCMV-mediated Inhibition of the Pro-apoptotic Bak Protein Is Required for Optimal In Vivo Replication
por: Fleming, Peter, et al.
Publicado: (2013)