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F-Spondin Deficient Mice Have a High Bone Mass Phenotype
F-spondin is a pericellular matrix protein upregulated in developing growth plate cartilage and articular cartilage during osteoarthritis. To address its function in bone and cartilage in vivo, we generated mice that were deficient for the F-spondin gene, Spon1. Spon1 (−) (/−) mice were viable and d...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038615/ https://www.ncbi.nlm.nih.gov/pubmed/24875054 http://dx.doi.org/10.1371/journal.pone.0098388 |