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F-Spondin Deficient Mice Have a High Bone Mass Phenotype

F-spondin is a pericellular matrix protein upregulated in developing growth plate cartilage and articular cartilage during osteoarthritis. To address its function in bone and cartilage in vivo, we generated mice that were deficient for the F-spondin gene, Spon1. Spon1 (−) (/−) mice were viable and d...

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Detalles Bibliográficos
Autores principales: Palmer, Glyn D., Attur, Mukundan G., Yang, Qing, Liu, James, Moon, Paxton, Beier, Frank, Abramson, Steven B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038615/
https://www.ncbi.nlm.nih.gov/pubmed/24875054
http://dx.doi.org/10.1371/journal.pone.0098388