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The PhoP-Dependent ncRNA Mcr7 Modulates the TAT Secretion System in Mycobacterium tuberculosis

The PhoPR two-component system is essential for virulence in Mycobacterium tuberculosis where it controls expression of approximately 2% of the genes, including those for the ESX-1 secretion apparatus, a major virulence determinant. Mutations in phoP lead to compromised production of pathogen-specif...

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Detalles Bibliográficos
Autores principales: Solans, Luis, Gonzalo-Asensio, Jesús, Sala, Claudia, Benjak, Andrej, Uplekar, Swapna, Rougemont, Jacques, Guilhot, Christophe, Malaga, Wladimir, Martín, Carlos, Cole, Stewart T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038636/
https://www.ncbi.nlm.nih.gov/pubmed/24874799
http://dx.doi.org/10.1371/journal.ppat.1004183