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The Netrin-1 receptor DCC is a regulator of maladaptive responses to chronic morphine administration

BACKGROUND: Opioids are the cornerstone of treatment for moderate to severe pain, but chronic use leads to maladaptations that include: tolerance, dependence and opioid-induced hyperalgesia (OIH). These responses limit the utility of opioids, as well as our ability to control chronic pain. Despite d...

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Detalles Bibliográficos
Autores principales:	Liang, De-Yong, Zheng, Ming, Sun, Yuan, Sahbaie, Peyman, Low, Sarah A, Peltz, Gary, Scherrer, Grégory, Flores, Cecilia, Clark, J David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038717/ https://www.ncbi.nlm.nih.gov/pubmed/24884839 http://dx.doi.org/10.1186/1471-2164-15-345

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