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Candidate genes and functional noncoding variants identified in a canine model of obsessive-compulsive disorder

BACKGROUND: Obsessive-compulsive disorder (OCD), a severe mental disease manifested in time-consuming repetition of behaviors, affects 1 to 3% of the human population. While highly heritable, complex genetics has hampered attempts to elucidate OCD etiology. Dogs suffer from naturally occurring compu...

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Detalles Bibliográficos
Autores principales: Tang, Ruqi, Noh, Hyun Ji, Wang, Dongqing, Sigurdsson, Snaevar, Swofford, Ross, Perloski, Michele, Duxbury, Margaret, Patterson, Edward E, Albright, Julie, Castelhano, Marta, Auton, Adam, Boyko, Adam R, Feng, Guoping, Lindblad-Toh, Kerstin, Karlsson, Elinor K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038740/
https://www.ncbi.nlm.nih.gov/pubmed/24995881
http://dx.doi.org/10.1186/gb-2014-15-3-r25