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Heritability of variation in glycaemic response to metformin: a genome-wide complex trait analysis
BACKGROUND: Metformin is a first-line oral agent used in the treatment of type 2 diabetes, but glycaemic response to this drug is highly variable. Understanding the genetic contribution to metformin response might increase the possibility of personalising metformin treatment. We aimed to establish t...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Lancet, Diabetes & Endocrinology
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038749/ https://www.ncbi.nlm.nih.gov/pubmed/24731673 http://dx.doi.org/10.1016/S2213-8587(14)70050-6 |