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Heritability of variation in glycaemic response to metformin: a genome-wide complex trait analysis

BACKGROUND: Metformin is a first-line oral agent used in the treatment of type 2 diabetes, but glycaemic response to this drug is highly variable. Understanding the genetic contribution to metformin response might increase the possibility of personalising metformin treatment. We aimed to establish t...

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Detalles Bibliográficos
Autores principales:	Zhou, Kaixin, Donnelly, Louise, Yang, Jian, Li, Miaoxin, Deshmukh, Harshal, Van Zuydam, Natalie, Ahlqvist, Emma, Spencer, Chris C, Groop, Leif, Morris, Andrew D, Colhoun, Helen M, Sham, Pak C, McCarthy, Mark I, Palmer, Colin N A, Pearson, Ewan R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Lancet, Diabetes & Endocrinology 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038749/ https://www.ncbi.nlm.nih.gov/pubmed/24731673 http://dx.doi.org/10.1016/S2213-8587(14)70050-6

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