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The role of cancer-associated fibroblasts, solid stress and other microenvironmental factors in tumor progression and therapy resistance

Tumors are not merely masses of neoplastic cells but complex tissues composed of cellular and noncellular elements. This review provides recent data on the main components of a dynamic system, such as carcinoma associated fibroblasts that change the extracellular matrix (ECM) topology, induce stemne...

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Detalles Bibliográficos
Autores principales: Kharaishvili, Gvantsa, Simkova, Dana, Bouchalova, Katerina, Gachechiladze, Mariam, Narsia, Nato, Bouchal, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038849/
https://www.ncbi.nlm.nih.gov/pubmed/24883045
http://dx.doi.org/10.1186/1475-2867-14-41