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Depolarization Controls TRAIL-Sensitization and Tumor-Selective Killing of Cancer Cells: Crosstalk with ROS

Conventional genotoxic anti-cancer drugs target the proliferative advantage of tumor cells over normal cells. This kind of approach lacks the selectivity of treatment to cancer cells, because most of the targeted pathways are essential for the survival of normal cells. As a result, traditional cance...

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Detalles Bibliográficos
Autores principales: Suzuki-Karasaki, Yoshihiro, Suzuki-Karasaki, Miki, Uchida, Mayumi, Ochiai, Toyoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038927/
https://www.ncbi.nlm.nih.gov/pubmed/24910845
http://dx.doi.org/10.3389/fonc.2014.00128