The ER mitochondria calcium cycle and ER stress response as therapeutic targets in amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive loss of upper and lower motor neurons. Although the etiology remains unclear, disturbances in calcium homoeostasis and protein folding are essential features of neurodegeneration in this disorder. Here, w...

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Detalles Bibliográficos
Autores principales: Tadic, Vedrana, Prell, Tino, Lautenschlaeger, Janin, Grosskreutz, Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039088/
https://www.ncbi.nlm.nih.gov/pubmed/24910594
http://dx.doi.org/10.3389/fncel.2014.00147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039088/
https://www.ncbi.nlm.nih.gov/pubmed/24910594
http://dx.doi.org/10.3389/fncel.2014.00147

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