Pharmacological correction of misfolding of ABC proteins()

The endoplasmic reticulum (ER) quality control system distinguishes between correctly and incorrectly folded proteins to prevent processing of aberrantly folded conformations along the secretory pathway. Non-synonymous mutations can lead to misfolding of ABC proteins and associated disease phenotype...

Descripción completa

Detalles Bibliográficos
Autores principales: Rudashevskaya, Elena L., Stockner, Thomas, Trauner, Michael, Freissmuth, Michael, Chiba, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Transporter Assays
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039138/
https://www.ncbi.nlm.nih.gov/pubmed/25027379
http://dx.doi.org/10.1016/j.ddtec.2014.03.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039138/
https://www.ncbi.nlm.nih.gov/pubmed/25027379
http://dx.doi.org/10.1016/j.ddtec.2014.03.009

Ejemplares similares