Tryptophan and Kynurenic Acid May Produce an Amplified Effect in Central Fatigue Induced by Chronic Sleep Disorder

Tryptophan (TRP) and its neuroactive metabolite, kynurenic acid (KYNA), are thought to play key roles in central fatigue, but the specifics are still unknown. To clarify their roles in the brain, we developed a rat model of central fatigue induced by chronic sleep disorder (CFSD) by disturbing the s...

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Detalles Bibliográficos
Autores principales: Yamashita, Masatoshi, Yamamoto, Takanobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039214/
https://www.ncbi.nlm.nih.gov/pubmed/24899814
http://dx.doi.org/10.4137/IJTR.S14084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039214/
https://www.ncbi.nlm.nih.gov/pubmed/24899814
http://dx.doi.org/10.4137/IJTR.S14084

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