Celecoxib suppresses hepatoma stemness and progression by up-regulating PTEN

Celecoxib, a COX-2 inhibitor and non-steroidal anti-inflammatory drug, can prevent several types of cancer, including hepatocellular carcinoma (HCC). Here we show that celecoxib suppressed the self-renewal and drug-pumping functions in HCC cells. Besides, celecoxib depleted CD44 + /CD133 + hepatic c...

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Detalles Bibliográficos
Autores principales: Chu, Tian-Huei, Chan, Hoi-Hung, Kuo, Hsiao-Mei, Liu, Li-Fen, Hu, Tsung-Hui, Sun, Cheuk-Kwan, Kung, Mei-Lang, Lin, Shih-Wei, Wang, E-Ming, Ma, Yi-Ling, Cheng, Kwan-Hung, Lai, Kwok Hung, Wen, Zhi-Hong, Hsu, Ping-I, Tai, Ming-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039225/
https://www.ncbi.nlm.nih.gov/pubmed/24721996

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039225/
https://www.ncbi.nlm.nih.gov/pubmed/24721996

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