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Strigolactone analogues induce apoptosis through activation of p38 and the stress response pathway in cancer cell lines and in conditionally reprogramed primary prostate cancer cells.

Strigolactones are a novel class of plant hormones produced in roots and regulate shoot and root development. We have previously shown that synthetic strigolactone analogues potently inhibit growth of breast cancer cells and breast cancer stem cells. Here we show that strigolactone analogues inhibit...

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Detalles Bibliográficos
Autores principales: Pollock, Claire B, McDonough, Sara, Wang, Victor S., Lee, Hyojung, Ringer, Lymor, Li, Xin, Prandi, Cristina, Lee, Richard J., Feldman, Adam S., Koltai, Hinanit, Kapulnik, Yoram, Rodriguez, Olga C, Schlegel, Richard, Albanese, Christopher, Yarden, Ronit I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039240/
https://www.ncbi.nlm.nih.gov/pubmed/24742967