Naïve and memory CD8 T cell pool homeostasis in advanced aging: impact of age and of antigen-specific responses to cytomegalovirus

Alterations in the circulating CD8+ T cell pool, with a loss of naïve and accumulation of effector/effector memory cells, are pronounced in older adults. However, homeostatic forces that dictate such changes remain incompletely understood. This observational cross-sectional study explored the basis...

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Detalles Bibliográficos
Autores principales: Vescovini, Rosanna, Fagnoni, Francesco Fausto, Telera, Anna Rita, Bucci, Laura, Pedrazzoni, Mario, Magalini, Francesca, Stella, Adriano, Pasin, Federico, Medici, Maria Cristina, Calderaro, Adriana, Volpi, Riccardo, Monti, Daniela, Franceschi, Claudio, Nikolich-Žugich, Janko, Sansoni, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039262/
https://www.ncbi.nlm.nih.gov/pubmed/24318918
http://dx.doi.org/10.1007/s11357-013-9594-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039262/
https://www.ncbi.nlm.nih.gov/pubmed/24318918
http://dx.doi.org/10.1007/s11357-013-9594-z

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