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Synergistic white matter protection with acute-on-chronic endotoxin and subsequent asphyxia in preterm fetal sheep

BACKGROUND: Perinatal asphyxia and exposure to intrauterine infection are associated with impaired neurodevelopment in preterm infants. Acute exposure to non-injurious infection and/or inflammation can either protect or sensitize the brain to subsequent hypoxia-ischemia. However, the effects of suba...

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Detalles Bibliográficos
Autores principales: van den Heuij, Lotte G, Mathai, Sam, Davidson, Joanne O, Lear, Christopher A, Booth, Lindsea C, Fraser, Mhoyra, Gunn, Alistair J, Bennet, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039331/
https://www.ncbi.nlm.nih.gov/pubmed/24886663
http://dx.doi.org/10.1186/1742-2094-11-89