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Voltage-independent sodium channels emerge for an expression of activity-induced spontaneous spikes in GABAergic neurons

BACKGROUND: Cerebral overexcitation needs inhibitory neurons be functionally upregulated to rebalance excitation vs. inhibition. For example, the intensive activities of GABAergic neurons induce spontaneous spikes, i.e., activity-induced spontaneous spikes (AISS). The mechanisms underlying AISS onse...

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Detalles Bibliográficos
Autores principales: Lu, Wei, Wen, Bo, Zhang, Fengyu, Wang, Jin-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039334/
https://www.ncbi.nlm.nih.gov/pubmed/24886791
http://dx.doi.org/10.1186/1756-6606-7-38