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Griseorhodins D–F, Neuroactive Intermediates and End Products of Post-PKS Tailoring Modification in Griseorhodin Biosynthesis

[Image: see text] The griseorhodins belong to a family of extensively modified aromatic polyketides that exhibit activities such as inhibition of HIV reverse transcriptase and human telomerase. The vast structural diversity of this group of polyketides is largely introduced by enzymatic oxidations,...

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Detalles Bibliográficos
Autores principales: Lin, Zhenjian, Zachariah, Malcolm M., Marett, Lenny, Hughen, Ronald W., Teichert, Russell W., Concepcion, Gisela P., Haygood, Margo G., Olivera, Baldomero M., Light, Alan R., Schmidt, Eric W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society and American Society of Pharmacognosy 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039362/
https://www.ncbi.nlm.nih.gov/pubmed/24786728
http://dx.doi.org/10.1021/np500155d