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Nucleotide degradation and ribose salvage in yeast

Nucleotide degradation is a universal metabolic capability. Here we combine metabolomics, genetics and biochemistry to characterize the yeast pathway. Nutrient starvation, via PKA, AMPK/SNF1, and TOR, triggers autophagic breakdown of ribosomes into nucleotides. A protein not previously associated wi...

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Detalles Bibliográficos
Autores principales: Xu, Yi-Fan, Létisse, Fabien, Absalan, Farnaz, Lu, Wenyun, Kuznetsova, Ekaterina, Brown, Greg, Caudy, Amy A, Yakunin, Alexander F, Broach, James R, Rabinowitz, Joshua D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039369/
https://www.ncbi.nlm.nih.gov/pubmed/23670538
http://dx.doi.org/10.1038/msb.2013.21