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Nucleotide degradation and ribose salvage in yeast
Nucleotide degradation is a universal metabolic capability. Here we combine metabolomics, genetics and biochemistry to characterize the yeast pathway. Nutrient starvation, via PKA, AMPK/SNF1, and TOR, triggers autophagic breakdown of ribosomes into nucleotides. A protein not previously associated wi...
Autores principales: | Xu, Yi-Fan, Létisse, Fabien, Absalan, Farnaz, Lu, Wenyun, Kuznetsova, Ekaterina, Brown, Greg, Caudy, Amy A, Yakunin, Alexander F, Broach, James R, Rabinowitz, Joshua D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Molecular Biology Organization
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039369/ https://www.ncbi.nlm.nih.gov/pubmed/23670538 http://dx.doi.org/10.1038/msb.2013.21 |
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