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Metabolic reconstruction identifies strain-specific regulation of virulence in Toxoplasma gondii

Increasingly, metabolic potential is proving to be a critical determinant governing a pathogen’s virulence as well as its capacity to expand its host range. To understand the potential contribution of metabolism to strain-specific infectivity differences, we present a constraint-based metabolic mode...

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Detalles Bibliográficos
Autores principales: Song, Carl, Chiasson, Melissa A, Nursimulu, Nirvana, Hung, Stacy S, Wasmuth, James, Grigg, Michael E, Parkinson, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039375/
https://www.ncbi.nlm.nih.gov/pubmed/24247825
http://dx.doi.org/10.1038/msb.2013.62