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Metabolic reconstruction identifies strain-specific regulation of virulence in Toxoplasma gondii
Increasingly, metabolic potential is proving to be a critical determinant governing a pathogen’s virulence as well as its capacity to expand its host range. To understand the potential contribution of metabolism to strain-specific infectivity differences, we present a constraint-based metabolic mode...
Autores principales: | Song, Carl, Chiasson, Melissa A, Nursimulu, Nirvana, Hung, Stacy S, Wasmuth, James, Grigg, Michael E, Parkinson, John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Molecular Biology Organization
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039375/ https://www.ncbi.nlm.nih.gov/pubmed/24247825 http://dx.doi.org/10.1038/msb.2013.62 |
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