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Population Pharmacokinetics of Azithromycin in Whole Blood, Peripheral Blood Mononuclear Cells, and Polymorphonuclear Cells in Healthy Adults

Azithromycin's extensive distribution to proinflammatory cells, including peripheral blood mononuclear cells (PBMCs) and polymorphonuclear cells (PMNs), may be important to its antimicrobial and anti-inflammatory properties. The need to simultaneously predict azithromycin concentrations in whol...

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Detalles Bibliográficos
Autores principales: Sampson, M R, Dumitrescu, T P, Brouwer, K L R, Schmith, V D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039392/
https://www.ncbi.nlm.nih.gov/pubmed/24599342
http://dx.doi.org/10.1038/psp.2013.80