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Recombinant TLR5 Agonist CBLB502 Promotes NK Cell-Mediated Anti-CMV Immunity in Mice

Prior work using allogeneic bone marrow transplantation (allo-BMT) models showed that peritransplant administration of flagellin, a toll-like receptor 5 (TLR5) agonist protected murine allo-BMT recipients from CMV infection while limiting graft-vs-host disease (GvHD). However, the mechanism by which...

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Detalles Bibliográficos
Autores principales: Hossain, Mohammad S., Ramachandiran, Sampath, Gewirtz, Andrew T., Waller, Edmund K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039429/
https://www.ncbi.nlm.nih.gov/pubmed/24879439
http://dx.doi.org/10.1371/journal.pone.0096165