Inherent Dynamics of Head Domain Correlates with ATP-Recognition of P2X4 Receptors: Insights Gained from Molecular Simulations

P2X receptors are ATP-gated ion channels involved in many physiological functions, and determination of ATP-recognition (AR) of P2X receptors will promote the development of new therapeutic agents for pain, inflammation, bladder dysfunction and osteoporosis. Recent crystal structures of the zebrafis...

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Detalles Bibliográficos
Autores principales: Huang, Li-Dong, Fan, Ying-Zhe, Tian, Yun, Yang, Yang, Liu, Yan, Wang, Jin, Zhao, Wen-Shan, Zhou, Wen-Chao, Cheng, Xiao-Yang, Cao, Peng, Lu, Xiang-Yang, Yu, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039465/
https://www.ncbi.nlm.nih.gov/pubmed/24878662
http://dx.doi.org/10.1371/journal.pone.0097528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039465/
https://www.ncbi.nlm.nih.gov/pubmed/24878662
http://dx.doi.org/10.1371/journal.pone.0097528

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