Anti-Fibrotic Actions of Interleukin-10 against Hypertrophic Scarring by Activation of PI3K/AKT and STAT3 Signaling Pathways in Scar-Forming Fibroblasts

BACKGROUND: The hypertrophic scar (HS) is a serious fibrotic skin condition and a major clinical problem. Interleukin-10 (IL-10) has been identified as a prospective scar-improving compound based on preclinical trials. Our previous work showed that IL-10 has anti-fibrotic effects in transforming gro...

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Detalles Bibliográficos
Autores principales: Shi, Jihong, Li, Jun, Guan, Hao, Cai, Weixia, Bai, Xiaozhi, Fang, Xiaobing, Hu, Xiaolong, Wang, Yaojun, Wang, Hongtao, Zheng, Zhao, Su, Linlin, Hu, Dahai, Zhu, Xiongxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039501/
https://www.ncbi.nlm.nih.gov/pubmed/24878845
http://dx.doi.org/10.1371/journal.pone.0098228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039501/
https://www.ncbi.nlm.nih.gov/pubmed/24878845
http://dx.doi.org/10.1371/journal.pone.0098228

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