Deletion of ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator) in β-Cells Causes Islet Transplant Failure with Impaired β-Cell Function

BACKGROUND: Replacing β-cells by islet-transplantation can cure type 1 diabetes, but up to 70% of β-cells die within 10 days of transplantation. ARNT (Aryl hydrocarbon Receptor Nuclear Translocator) regulates β-cell function, and potentially survival. Lack of ARNT impairs the ability of β-cells to r...

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Detalles Bibliográficos
Autores principales: Lalwani, Amit, Stokes, Rebecca A., Lau, Sue Mei, Gunton, Jenny E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039512/
https://www.ncbi.nlm.nih.gov/pubmed/24878748
http://dx.doi.org/10.1371/journal.pone.0098435

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039512/
https://www.ncbi.nlm.nih.gov/pubmed/24878748
http://dx.doi.org/10.1371/journal.pone.0098435

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