SJL Mice Infected with Acanthamoeba castellanii Develop Central Nervous System Autoimmunity through the Generation of Cross-Reactive T Cells for Myelin Antigens

We recently reported that Acanthamoeba castellanii (ACA), an opportunistic pathogen of the central nervous system (CNS) possesses mimicry epitopes for proteolipid protein (PLP) 139–151 and myelin basic protein 89–101, and that the epitopes induce experimental autoimmune encephalomyelitis (EAE) in SJ...

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Detalles Bibliográficos
Autores principales: Massilamany, Chandirasegaran, Marciano-Cabral, Francine, da Rocha-Azevedo, Bruno, Jamerson, Melissa, Gangaplara, Arunakumar, Steffen, David, Zabad, Rana, Illes, Zsolt, Sobel, Raymond A., Reddy, Jay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039519/
https://www.ncbi.nlm.nih.gov/pubmed/24879066
http://dx.doi.org/10.1371/journal.pone.0098506

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039519/
https://www.ncbi.nlm.nih.gov/pubmed/24879066
http://dx.doi.org/10.1371/journal.pone.0098506

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