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Neuroproteome Changes after Ischemia/Reperfusion Injury and Tissue Plasminogen Activator Administration in Rats: A Quantitative iTRAQ Proteomics Study

The thrombolytic, recombinant tissue plasminogen activator (rt-PA) is the only approved therapy for acute ischemic stroke (AIS). When administered after AIS, rt-PA has many adverse pleiotropic actions, which are currently poorly understood. The identification of proteins showing differential express...

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Detalles Bibliográficos
Autores principales: Merali, Zamir, Gao, Meah MingYang, Bowes, Tim, Chen, Jian, Evans, Kenneth, Kassner, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039533/
https://www.ncbi.nlm.nih.gov/pubmed/24879061
http://dx.doi.org/10.1371/journal.pone.0098706