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HIF1α and HIF2α Exert Distinct Nutrient Preferences in Renal Cells

BACKGROUND: Hypoxia Inducible Factors (HIF1α and HIF2α) are commonly stabilized and play key roles related to cell growth and metabolic programming in clear cell renal cell carcinoma. The relationship of these factors to discretely alter cell metabolic activities has largely been described in cancer...

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Detalles Bibliográficos
Autores principales: Arreola, Alexandra, Cowey, C. Lance, Coloff, Jonathan L., Rathmell, Jeffrey C., Rathmell, W. Kimryn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039535/
https://www.ncbi.nlm.nih.gov/pubmed/24879016
http://dx.doi.org/10.1371/journal.pone.0098705