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Nerve growth factor improves functional recovery by inhibiting endoplasmic reticulum stress-induced neuronal apoptosis in rats with spinal cord injury

BACKGROUND: Endoplasmic reticulum (ER) stress-induced apoptosis plays a major role in various diseases, including spinal cord injury (SCI). Nerve growth factor (NGF) show neuroprotective effect and improve the recovery of SCI, but the relations of ER stress-induced apoptosis and the NGF therapeutic...

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Detalles Bibliográficos
Autores principales: Zhang, Hongyu, Wu, Fenzan, Kong, Xiaoxia, Yang, Jie, Chen, Huijun, Deng, Liancheng, Cheng, Yi, Ye, Libing, Zhu, Sipin, Zhang, Xie, Wang, Zhouguang, Shi, Hongxue, Fu, Xiaobing, Li, Xiaokun, Xu, Huazi, Lin, Li, Xiao, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039547/
https://www.ncbi.nlm.nih.gov/pubmed/24884850
http://dx.doi.org/10.1186/1479-5876-12-130