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Platelet-derived growth factor (PDGF)-C inhibits neuroretinal apoptosis in a murine model of focal retinal degeneration

Platelet-derived growth factor (PDGF)-C is a member of the PDGF family and is critical for neuronal survival in the central nervous system. We studied the possible survival and anti-apoptotic effects of PDGF-C on focal retinal lesions in Ccl2(−/−)/Cx3cr1(−/−) on C57BL/6N [Crb1(rd8)] (DKO rd8) backgr...

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Detalles Bibliográficos
Autores principales: Wang, Yujuan, Abu-Asab, Mones S., Yu, Cheng-Rong, Tang, Zhongshu, Shen, Defen, Tuo, Jingsheng, Li, Xuri, Chan, Chi-Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039574/
https://www.ncbi.nlm.nih.gov/pubmed/24709779
http://dx.doi.org/10.1038/labinvest.2014.60