Inhibition of neutral sphingomyelinases in skeletal muscle attenuates fatty-acid induced defects in metabolism and stress

BACKGROUND: Chronic metabolic overload leads to insulin resistance in a variety of tissues. It has been shown that exposure to saturated fatty acid palmitate can cause insulin resistance in skeletal muscle cells. Fatty acid induced synthesis of ceramide is considered to be one of the major causes fo...

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Detalles Bibliográficos
Autores principales: Verma, Mahesh Kumar, Yateesh, Aggunda Nagaraju, Neelima, Korrapati, Pawar, Niketa, Sandhya, Kandoor, Poornima, Jayaram, Lakshmi, Mudigere N, Yogeshwari, Sivakumaran, Pallavi, Puttrevana M, Oommen, Anup M, Somesh, Baggavalli P, Jagannath, Madanahalli R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039661/
https://www.ncbi.nlm.nih.gov/pubmed/24892004
http://dx.doi.org/10.1186/2193-1801-3-255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039661/
https://www.ncbi.nlm.nih.gov/pubmed/24892004
http://dx.doi.org/10.1186/2193-1801-3-255

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