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Effects of o-vanillin on K(+) transport of red blood cells from patients with sickle cell disease
Aromatic aldehydes like o-vanillin were designed to reduce the complications of sickle cell disease (SCD) by interaction with HbS, to reduce polymerisation and RBC sickling. Present results show that o-vanillin also directly affects RBC membrane permeability. Both the K(+)–Cl(−) cotransporter (KCC)...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039999/ https://www.ncbi.nlm.nih.gov/pubmed/24594314 http://dx.doi.org/10.1016/j.bcmd.2014.02.004 |