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Effects of o-vanillin on K(+) transport of red blood cells from patients with sickle cell disease

Aromatic aldehydes like o-vanillin were designed to reduce the complications of sickle cell disease (SCD) by interaction with HbS, to reduce polymerisation and RBC sickling. Present results show that o-vanillin also directly affects RBC membrane permeability. Both the K(+)–Cl(−) cotransporter (KCC)...

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Detalles Bibliográficos
Autores principales:	Hannemann, A., Cytlak, U.M.C., Gbotosho, O.T., Rees, D.C., Tewari, S., Gibson, J.S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Academic Press 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4039999/ https://www.ncbi.nlm.nih.gov/pubmed/24594314 http://dx.doi.org/10.1016/j.bcmd.2014.02.004

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