Crk1/2 and CrkL form a hetero-oligomer and functionally complement each other during podocyte morphogenesis

Activation of the slit diaphragm protein Nephrin induces actin cytoskeletal remodeling resulting in lamellipodia formation in podocytes in vitro in a phosphatidylinositol-3 kinase, focal adhesion kinase, Cas, and Crk1/2-dependent fashion. In mice, podocyte-specific deletion of Crk1/2 prevents or att...

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Detalles Bibliográficos
Autores principales: George, Britta, Fan, Qingfeng, Dlugos, Christopher P., Soofi, Abdulsalam A., Zhang, Jidong, Verma, Rakesh, Park, Tae-Ju, Wong, Hetty, Curran, Tom, Nihalani, Deepak, Holzman, Lawrence B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040156/
https://www.ncbi.nlm.nih.gov/pubmed/24499776
http://dx.doi.org/10.1038/ki.2013.556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040156/
https://www.ncbi.nlm.nih.gov/pubmed/24499776
http://dx.doi.org/10.1038/ki.2013.556

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