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Safety of artemether-lumefantrine exposure in first trimester of pregnancy: an observational cohort

BACKGROUND: There is limited data available regarding safety profile of artemisinins in early pregnancy. They are, therefore, not recommended by WHO as a first-line treatment for malaria in first trimester due to associated embryo-foetal toxicity in animal studies. The study assessed birth outcome a...

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Detalles Bibliográficos
Autores principales: Mosha, Dominic, Mazuguni, Festo, Mrema, Sigilbert, Sevene, Esperanca, Abdulla, Salim, Genton, Blaise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040412/
https://www.ncbi.nlm.nih.gov/pubmed/24884890
http://dx.doi.org/10.1186/1475-2875-13-197