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Pol III Promoters to Express Small RNAs: Delineation of Transcription Initiation

Pol III promoters such as U6 are commonly used to express small RNAs, including small interfering RNA, short hairpin RNA, and guide RNA, for the clustered regularly interspaced short palindromic repeats genome-editing system. However, whether the small RNAs were precisely expressed as desired has no...

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Detalles Bibliográficos
Autores principales: Ma, Hongming, Wu, Yonggan, Dang, Ying, Choi, Jang-Gi, Zhang, Junli, Wu, Haoquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040628/
https://www.ncbi.nlm.nih.gov/pubmed/24803291
http://dx.doi.org/10.1038/mtna.2014.12