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Ibuprofen enhances the anticancer activity of cisplatin in lung cancer cells by inhibiting the heat shock protein 70

Hsp70 is often overexpressed in cancer cells, and the selective cellular survival advantage that it confers may contribute to the process of tumour formation. Thus, the pharmacological manipulation of Hsp70 levels in cancer cells may be an effective means of preventing the progression of tumours. We...

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Detalles Bibliográficos
Autores principales: Endo, H, Yano, M, Okumura, Y, Kido, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040650/
https://www.ncbi.nlm.nih.gov/pubmed/24481441
http://dx.doi.org/10.1038/cddis.2013.550